Staphylococcus epidermidis bacteriocin A37 kills natural competitors with a unique mechanism of action
Many bacteria produce substances to gain an advantage over competitors in their highly competitive natural environment. Researchers at the University Hospital Bonn (UKB), the University of Bonn and the German Center for Infection Research (DZIF) have discovered a new antibiotic-active peptide from the group of so-called lantibiotics—namely epilancin A37. It is produced by staphylococci that colonise the skin and act specifically against their main competitors there, the corynebacteria. This specificity is presumably mediated by a very special mechanism of action, which the researchers were able to decipher in detail. Their results have now been published in the renowned ISME Journal.